Doctrine doesn't emerge in a vacuum. It grows from a broader culture — philosophy of science, history of technology, complex systems economics, epistemology of measurement. 41 explorations.
Of four digital sovereignty layers, only the energy layer is allocated, not composed. AI enters macro-industrial governance.
May 2026
Seven layers, three verdicts: arbitration doctrine of composite sovereignty for AI in regulated European environments. Silicon changes political nature.
May 2026
AI kilowatt-hour allocation is triply distributed (market, contracts, local blockages) without deliberative procedure. Conditions for a sectoral protocol.
May 2026
The CVE-2026-31431 (Copy Fail) case on WSL2 kernel 6.6.87.2 as empirical terrain for the promotion gate between technical artifact and normative dependency.
April 2026
JEPA and latent predictive architectures: geometry of predictability, anti-collapse constraints, the unmet threshold of biographical memory.
April 2026
ToxTwin V2.4: endpoint tri-router, enriched Ames ISS and hERG ChEMBL corpora. Tox21 mean AUC 0.898, Ames 0.853, hERG 0.800. Lessons from a controlled cycle.
April 2026
Full toxicological report on doxorubicin via ToxTwin V1.3: 14 Tox21 endpoints, Ames, hERG, mechanistic interpretation, and literature concordance.
April 2026
ToxTwin V2.3 technical synthesis: 14 endpoints, AUC 0.867, corrected biases, IR calibration, composite AD, V2.4 plan.
April 2026
ToxTwin V2.3 user guide for toxicologists and researchers. SMILES, 14 endpoints, calibrated scores, applicability domain, FAQ.
April 2026
Why agentic AI is fundamentally an enterprise architecture problem. Five structural functions of EDA for situated, auditable, governable AI agents.
April 2026
Gap between massive deployment and real adoption of Microsoft 365 Copilot. 3.3% penetration, negative NPS, generative shadow IT.
March 2026
ToxTwin FastAPI API documentation. Aspirin and ibuprofen validation tests, differential NR-PPAR-gamma signal, ScoreResponse format.
March 2026
Dreyfus, Searle, and the language/representation confusion. Explicit, implicit, and pipeline encoding. The data scientist layer.
March 2026
Biological transduction vs mediated encoding. Symbol grounding problem. Molyneux's problem, Mary's argument. Three grounding levels.
March 2026
Memory as polycentric graph. Biographical edge vs statistical edge. World models: decisive advance but insufficient threshold.
March 2026
Full article (28 pp.). Encoding, transduction, stratified grounding, polycentric memory graph, biographical edge, world models.
March 2026
Full ToxTwin workflow on an unknown candidate out of domain (Tanimoto 0.153). SR-p53 (32.6%) and SR-ARE (25.5%) signals.
March 2026
End-to-end ToxGNN-V1 pipeline (Mean AUC 0.857 on Tox21). Medallion architecture, NER extraction via Phi-4 14B, MDR and EU AI Act.
March 2026
Why most Bayesian implementations in health AI are frequentism dressed up as a probabilistic graph. Calibration, drift, and the HR argument.
March 2026
AI explainability in medicine is a relational predicate, not an absolute. Measured, audited, monitored reliability over illusory transparency.
March 2026
Analysis of AI's physical constraints: energy, water, data, silicon. $200B in GPUs, <10% adoption, Jevons rebound effect.
February 2026
Six-dimension eligibility framework: decision topology, time balance, uncertainty reduction, coupling, TCO, reversibility.
February 2026
Structural analysis of AI-induced clinical cognitive load: techno-solutionism, collective decision-making, strained IT departments, TweenMe encapsulation.
February 2026
GVI/PCI analysis (MIT CPO) of the French sovereign cloud market: hyperscalers, SecNumCloud, territorialised hybridisation, risk matrix.
July 2025
Impressive technical progress does not exempt from economic and clinical proof. The missing independent health-economic evidence for AI in healthcare.
July 2025
Answers to fundamental quantum computing questions: storage, computing basis, memory architecture and RSA decryption.
March 2025
The quantum stability challenge: bosonic cat-qubits, Amazon's Ocelot chip and Alice & Bob's TomCat architecture.
March 2025
Majorana fermions — particles that are their own antiparticle — as candidates for fault-tolerant topological qubits.
March 2025
Comparison of qubit architectures: superconducting, trapped ions, topological, neutral atoms, photonic, silicon spin.
February 2025
Quantum mechanics fundamentals: qubits, superposition, entanglement, Bloch sphere, observables and wave function collapse.
February 2025
AI as research accelerator in bio-industries. Data quality, HDLSS, cybersecurity, AlphaFold v3 limitations.
January 2025
Why the patient digital twin concept lacks defensible scientific content — and why the answer is a generator.
January 2025
From buzzword to operational discipline. Analytical framework, maturity models, ontological intelligence, cybersecurity and TweenMe.
January 2025
Critical analysis of agentic AI frameworks. Historical roots, structural novelties, persistent challenges, and the cybersecurity blind spot.
November 2024
What emergency medicine and philosophy of mind say about consciousness — and its implications for AI.
January 2024
Perceptrons, transformers, emergent complexity through massification. The brain is fractal, not a lasagna dish.
April 2023
COVID-19 excess mortality in nursing homes: geriatric frailty, polypharmacy, ICU limits, palliative care ethics.
April 2020
Physiopathology of SARS-CoV-2: ACE2 binding, TMPRSS2 activation, cytokine storm, ARDS, sepsis, and therapeutic approaches (March 2020).
March 2020
RT-PCR mechanics, ELISA immunological tests, sensitivity/specificity trade-offs, and why massive testing alone cannot contain a pandemic.
March 2020
Fundamental virology refresher: viral structure, envelope, genetic payload, replication cycle, mutations and recombination of SARS-CoV-2.
March 2020
Analysis of frugal innovation in a VUCA world: short cycles, trial-and-error culture, MVP, and the banking industry case.
September 2016